Assume: Leukemia occurs at an incidence of 1 in 10,000. Benzene is a known carcinogen which causes Leukemia and has been found in toxic levels in the homes of a community of 1200 people.
Question: How many cases of Leukemia would be necessary to reject the null hypothesis. That is, to suggest that statistically, the cases are more likely due to benzene exposure rather than chance.